Applications of Microdialysis in Pharmaceutical Science by Tung-Hu Tsai PDF

By Tung-Hu Tsai

ISBN-10: 0470409282

ISBN-13: 9780470409282

Discover new and rising purposes for microdialysis in drug evaluation

Microdialysis is a hugely priceless sampling software that may be utilized in vivo to degree loose, unbound analyte concentrations positioned in interstitial and extracellular areas. This booklet explores the entire diversity of medical functions for microdialysis, concentrating on its use in several organ and tissue platforms for pharmacokinetic and pharmacodynamic reviews. Readers achieve a whole realizing of the underlying technological know-how of microdialysis, present suggestions and practices, in addition to its many purposes in pharmaceutical research.

Applications of Microdialysis in Pharmaceutical technology begins with an advent to easy rules after which covers analytical concerns, pharmacodynamic and pharmacokinetic stories, medical points, and certain functions. issues include:

  • Role of microdialysis in drug improvement, together with the most important sampling issues and functions for worried procedure diseases

  • Continuous size of glucose concentrations in diabetics

  • Applications for scientific evaluate and uncomplicated learn on organ structures, together with tracking exogenous and endogenous compounds within the lungs

  • Pharmacokinetic and pharmacodynamic overview of anticancer drugs

  • Comparison of microdialysis with imaging ways to judge in vivo drug distribution

  • Special purposes of microdialysis in reviews of mobile tradition assays, drug-drug interactions, and environmental monitoring

Throughout the publication, readers will locate uncomplicated versions that make clear complicated recommendations and easy-to-follow examples that advisor them via key purposes in pharmaceutical study. briefly, this publication permits pharmaceutical researchers to take complete good thing about microdialysis concepts for the preclinical and scientific assessment of gear and lots more and plenty more.

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Applications of Microdialysis in Pharmaceutical Science by Tung-Hu Tsai

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